Aggregated Target2NP view across data sources — aggregated

Return compound-target pairs (keyed by InChIKey + UniProt ID) supported by interaction records in at least min_sources source databases. Optionally extends each pair with DrugCLIP / SEA prediction support.

Usage

aggregated_target2np(
  search = NULL,
  target_organism = NULL,
  min_sources = 2L,
  include_predictions = FALSE,
  page = 1L,
  page_size = 20L
)

Arguments

search: Free-text search query.
target_organism: Optional target organism filter.
min_sources: Minimum number of source databases supporting the pair (1-5, default 2).
include_predictions: If TRUE, also count DrugCLIP and SEA predictions as additional supporting sources.
page: Page number (default 1).
page_size: Results per page (default 20, max 50).

Value

A tibble::tibble() of aggregated pairs with attribute "total".

Examples

if (FALSE) { # \dontrun{
aggregated_target2np(search = "quercetin")
aggregated_target2np(search = "TP53", min_sources = 3,
                     include_predictions = TRUE)
} # }