Identify hub genes by degree centrality — identify_hub_genes • unitcm

Calculates degree centrality for all nodes in a PPI network and returns the top-ranked hub genes.

Usage

identify_hub_genes(graph, top_n = 10L)

Arguments

graph: An igraph object (from build_ppi_network()).
top_n: Number of top hub genes to return. Default 10.

Value

A named numeric vector of degree centrality values for the top hub genes, sorted in descending order.

Examples

if (FALSE) { # \dontrun{
ppi <- query_string_ppi(c("TP53", "BRCA1", "EGFR", "VEGFA", "TNF"))
g <- build_ppi_network(ppi, c("TP53", "BRCA1", "EGFR", "VEGFA", "TNF"))
hubs <- identify_hub_genes(g, top_n = 5)
print(hubs)
} # }