Compute per-node closest distance to another gene set

For each node in setA, finds the shortest-path distance to the nearest node in setB. Useful for identifying which specific genes are close to or far from a disease module.

Usage

per_node_distance(graph, setA, setB)

Arguments

graph

An igraph object.

setA

Character vector of gene symbols (query nodes).

setB

Character vector of gene symbols (target set).

Value

A named numeric vector where names are genes from setA and values are the closest distance to any gene in setB. Genes not present in the network are omitted. Returns an empty named numeric vector if no paths exist.

Examples

if (FALSE) { # \dontrun{
g <- build_ppi_network(ppi_df, all_genes)
per_node_distance(g, c("TP53", "BRCA1"), c("EGFR", "VEGFA"))
} # }