Search Target2NP compound-target interactions — search

Query the UniTCM Target2NP database of natural-product to protein-target interactions, combining records from experimental sources such as BindingDB, HERB2, NPASS, BATMAN, and others.

Usage

search_target2np(
  search = NULL,
  search_field = c("all", "gene_symbol", "compound_name", "uniprot_id", "inchikey",
    "pubchem_cid", "chembl_id"),
  search_mode = c("exact", "fuzzy"),
  source_db = NULL,
  evidence_level = NULL,
  evidence_label = NULL,
  target_organism = NULL,
  interaction_type = NULL,
  activity_type = NULL,
  page = 1L,
  page_size = 20L,
  all_pages = FALSE
)

Arguments

search: Free-text search query.
search_field: Field to restrict the search to. One of "all", "gene_symbol", "compound_name", "uniprot_id", "inchikey", "pubchem_cid", or "chembl_id".
search_mode: "exact" (case-insensitive equality) or "fuzzy" (substring match).
source_db: Filter by source database (e.g. "BindingDB").
evidence_level: Filter by evidence level (integer 1-4 as string).
evidence_label: Filter by evidence label.
target_organism: Filter by target organism (e.g. "Homo sapiens").
interaction_type: Filter by interaction type.
activity_type: Filter by activity type (e.g. "IC50", "Ki").
page: Page number (default 1).
page_size: Results per page (default 20, max 100).
all_pages: If TRUE, fetch all pages.

Value

A tibble::tibble() of interaction records with attribute "total".

Examples

if (FALSE) { # \dontrun{
search_target2np(search = "quercetin")
search_target2np(search = "TP53", search_field = "gene_symbol",
                 source_db = "BindingDB")
} # }