Compute mean internal distance of a gene set

Calculates the mean shortest-path distance between all pairs of nodes within the given gene set.

Usage

self_distance(graph, gene_set)

Arguments

graph

An igraph object.

gene_set

Character vector of gene symbols.

Value

A single numeric value — the mean pairwise distance within the set. Returns 0 if the set has fewer than 2 nodes, and NaN if no valid paths exist.

Examples

if (FALSE) { # \dontrun{
g <- build_ppi_network(ppi_df, all_genes)
self_distance(g, c("TP53", "BRCA1", "EGFR"))
} # }